21 days in Spain, Rome & London Itinerary

Madrid is known for its cultural and artistic heritage, lively nightlife, and a dynamic culinary scene.

Your day by day itinerary now includes Metropolis Building, Palacio De Cristal, Museo Nacional Centro de Arte Reina Sofia, and other attractions you added. Satisfy your inner culture vulture at Prado National Museum and Plaza Mayor. Appreciate the collections at Museo Nacional Thyssen-Bornemisza and Alcazar - Biblioteca de Castilla-La Mancha. You'll find plenty of places to visit near Madrid: Toledo (Church of Santo Tomé & Casco Historico de Toledo). There's much more to do: steep yourself in history at Royal Palace of Madrid, stroll around Parque del Retiro, explore the world behind art at Museo Sorolla, and take in the exciting artwork at Cava Baja Gallery.

Plan my day in Madrid using traveler tips and tourist information provided by Inspirock.

Curitiba, Brazil to Madrid is an approximately 16-hour flight. The time zone difference moving from Brasilia Standard Time (BRT) to Central European Standard Time (CET) is 4 hours. Expect slightly colder temperatures when traveling from Curitiba in April; daily highs in Madrid reach 22°C and lows reach 9°C. Finish your sightseeing early on the 11th (Tue) to allow enough time to fly to Bilbao.

A city of stunning architectural and artistic heritage, Bilbao is situated on the banks of the Nervión River.

Kick off your visit on the 11th (Tue): take your sightseeing to a higher altitude at Monte Serantes, snap pictures at La Salve zubia, and then explore the world behind art at Guggenheim Museum Bilbao. Keep things going the next day: take in the spiritual surroundings of Parroquia de San Vicente Mártir de Abando, then explore the historical opulence of Palacio de la Diputacion, and then admire the masterpieces at Bilbao Fine Arts Museum.

To see reviews, more things to do, traveler tips, and other tourist information, use the Bilbao trip itinerary planning app.

You can fly from Madrid to Bilbao in 2.5 hours. Other options are to drive; or take a bus. In April in Bilbao, expect temperatures between 21°C during the day and 10°C at night. You will have some time to spend on the 13th (Thu) before leaving for Barcelona.

Barcelona, the country’s second-largest city, is a cosmopolitan urban center known for its throbbing youthful energy and stellar architecture.

Discover out-of-the-way places like Museu Nacional d'Art de Catalunya - MNAC and Hash Marihuana & Hemp Museum. Get some cultural insight at Basilica de la Sagrada Familia and Joan Miro Foundation. There's much more to do: take a stroll through El Born, admire the landmark architecture of Casa Batllo, take an in-depth tour of Museu d'Història de Barcelona MUHBA, and visit Las Ramblas.

To find reviews, maps, and other tourist information, refer to the Barcelona trip itinerary maker tool.

You can fly from Bilbao to Barcelona in 3 hours. Other options are to drive; or take a train. In April in Barcelona, expect temperatures between 22°C during the day and 13°C at night. Wrap up your sightseeing on the 16th (Sun) to allow time to fly to Rome.

Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.

Your day by day itinerary now includes Sistine Chapel as well as Vatican Museums. You'll explore the less-touristy side of things at Cupola di San Pietro and Villa Borghese. Satisfy your inner culture vulture at Colosseum and Centro Storico Associazione Centro Storico. The adventure continues: admire the striking features of Pantheon, explore the world behind art at Museo Nazionale Romano - Palazzo Massimo alle Terme, take in the architecture and atmosphere at Basilica di San Pietro in Vincoli, and see the interesting displays at Stanze di Raffaello.

To find photos, where to stay, more things to do, and other tourist information, go to the Rome holiday maker tool.

You can fly from Barcelona to Rome in 5 hours. Alternatively, you can drive; or take a train. In April, daytime highs in Rome are 24°C, while nighttime lows are 11°C. On the 20th (Thu), you'll have the morning to explore before heading off to London.

Vibrant and noisy, London is one of the world’s leading cities, an international capital of culture, education, fashion, music, finance, trade, and politics.

Museum-lovers will get to explore National Gallery and Wallace Collection. Get a sense of the local culture at Museum of London and Natural History Museum. Next up on the itinerary: take in the spiritual surroundings of Westminster Abbey, don't miss a visit to Big Ben, view the masterpieces at The Courtauld Gallery, and explore the landscape on two wheels at BrakeAway Bike Tours.

To see traveler tips, more things to do, photos, and other tourist information, read London trip planner.

Fly from Rome to London in 5.5 hours. Alternatively, you can take a train; or do a combination of car and train. The time zone changes from Central European Standard Time to Greenwich Mean Time, which is usually a -1 hour difference. Plan for a bit cooler temperatures traveling from Rome in April, with highs in London at 15°C and lows at 5°C. Wrap up your sightseeing on the 25th (Tue) to allow time to fly back home.