21 days in Italy Itinerary

The landscape surrounding Catania, a medieval city on Sicily's eastern coast, is dominated by Mount Etna, the tallest active volcano in Europe.

Get ready for a full day of sightseeing on the next day: see Off-Road Tours, take an in-depth tour of Monastero dei Benedettini, test your problem-solving skills at popular escape rooms, then stroll around Villa Comunale, then don't miss a visit to Corso Umberto, and finally take in the pleasant sights at Piazza IX Aprile.

Before you visit Catania, use our trip planner to discover what you can do and see there.

Alexandria, Egypt to Catania is an approximately 11-hour flight. You can also do a combination of car and ferry. The time zone difference when traveling from Alexandria to Catania is minus 1 hour. Traveling from Alexandria in April, expect Catania to be little chillier, temps between 23°C and 9°C. Finish your sightseeing early on the 19th (Wed) so you can fly to Siena.

Siena, a medieval Tuscan city, features numerous attractions, including a historic town center, alleyways, towers, and well-preserved buildings.

Start off your visit on the 20th (Thu): admire the masterpieces at Complesso Museale Santa Maria della Scala, take in panoramic vistas at Torre del Mangia, make a trip to Centro Storico di Siena, then take in the architecture and atmosphere at Duomo di Siena, then don't miss a visit to Piazza del Campo, and finally indulge in some culinary diversions at a local gastronomic tour.

To see photos, where to stay, traveler tips, and other tourist information, read our Siena online trip itinerary planner.

Traveling by flight from Catania to Siena takes 3 hours. Alternatively, you can do a combination of car and ferry; or do a combination of train and ferry. April in Siena sees daily highs of 23°C and lows of 9°C at night. Wrap up your sightseeing on the 20th (Thu) early enough to drive to Florence.

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.

Kick off your visit on the 21st (Fri): admire the natural beauty at The Boboli Gardens, make a trip to Piazzale Michelangelo, snap pictures at Ponte Vecchio, get to know the fascinating history of Piazza del Duomo, then take in the spiritual surroundings of Cathedral of Santa Maria del Fiore, and finally enjoy breathtaking views from Campanile di Giotto. Get ready for a full day of sightseeing on the next day: examine the collection at Pitti Palace, steep yourself in history at Basilica of Santa Croce, admire the masterpieces at Florence Academy of Fine Arts, then appreciate the extensive heritage of Centro Storico, and finally don't miss a visit to Piazza della Signoria.

To see reviews, traveler tips, photos, and more tourist information, you can read our Florence trip itinerary app.

You can drive from Siena to Florence in 1.5 hours. Other options are to take a bus; or take a train. April in Florence sees daily highs of 22°C and lows of 11°C at night. Finish your sightseeing early on the 22nd (Sat) so you can drive to Cinque Terre.

Made up of five picturesque towns on the Ligurian coast, Cinque Terre is Italy's answer to the French Riviera.

Start off your visit on the 23rd (Sun): hike along Footpath Monterosso - Vernazza, get into the urban bustle at Vernazza, then see some colorful creatures with Angelo's Boat Tours - Cinque Terre Boat Tours, and finally take in the architecture and atmosphere at Convento dei Cappuccini e Chiesa di San Francesco.

Plan a Cinque Terre trip in moments using our itinerary builder.

Traveling by car from Florence to Cinque Terre takes 2.5 hours. Alternatively, you can take a train. In April, plan for daily highs up to 22°C, and evening lows to 9°C. Finish your sightseeing early on the 23rd (Sun) so you can take a train to Genoa.

Once the most important harbor in the Mediterranean Sea, Genoa has a long history as a rich and powerful trade center in northern Italy.

Start off your visit on the 24th (Mon): contemplate in the serene atmosphere at Cattedrale di San Lorenzo - Duomo di Genova, appreciate the extensive heritage of Via Giuseppe Garibaldi, take in panoramic vistas at Spianata Castelletto, don't miss a visit to Piazza De Ferrari, then see the interesting displays at Dialogo nel Buio, and finally enjoy the sand and surf at Baia del Silenzio. Here are some ideas for day two: appreciate the extensive heritage of Passeggiata Anita Garibaldi a Nervi, take a stroll through Boccadasse, then see the interesting displays at Galata Museo del Mare, then admire nature's wide array of creatures at Aquarium of Genoa, and finally take in the waterfront at Old Port.

For photos, other places to visit, ratings, and more tourist information, refer to the Genoa trip planner.

You can take a train from Cinque Terre to Genoa in 2 hours. Alternatively, you can drive; or do a combination of train and bus. Traveling from Cinque Terre in April, Genoa is a bit warmer at night with lows of 14°C. Wrap up your sightseeing on the 25th (Tue) to allow time to drive to Turin.

A city of technology and industry, Turin is in northwestern Italy, a one-hour drive from the French border and slightly more than that from the Mediterranean Sea.

Start off your visit on the 26th (Wed): don't miss a visit to Piazza Castello, make a trip to Piazza San Carlo, take in nature's colorful creations at Parco del Valentino, examine the collection at Museo Nazionale dell'Automobile, then take in the architecture and atmosphere at Basilica di Superga, and finally test your team's savvy at popular escape rooms.

To see other places to visit, traveler tips, reviews, and other tourist information, go to the Turin trip itinerary planner.

Getting from Genoa to Turin by car takes about 2 hours. Other options: take a bus; or take a train. Traveling from Genoa in April, things will get slightly colder in Turin: highs are around 17°C and lows about 9°C. Finish your sightseeing early on the 26th (Wed) so you can take a train to Verona.

The famous setting for Shakespeare's star-crossed lovers, Romeo and Juliet, Verona is one of northern Italy's main tourist destinations, largely owing to its incredibly rich artistic heritage.

Kick off your visit on the 27th (Thu): make a trip to Piazza dei Signori, snap pictures at Ponte Pietra, don't miss a visit to Piazza Bra, then examine the collection at Casa di Giulietta, then contemplate in the serene atmosphere at Basilica di San Zeno Maggiore, and finally take in the views from Ponte Scaligero. On your second day here, admire nature's wide array of creatures at Parco Natura Viva, then admire the natural beauty at Parco Giardino Sigurta, then get to know the fascinating history of Borghetto sul Mincio, and finally admire the masterpieces at Palazzo Te.

Plan a Verona trip in moments using our itinerary builder.

You can take a train from Turin to Verona in 3 hours. Other options are to drive; or take a bus. Traveling from Turin in April, expect nights in Verona to be about the same, around 9°C, while days are a bit warmer, around 23°C. Finish up your sightseeing early on the 28th (Fri) so you can go by car to Venice.

Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.

Start off your visit on the 29th (Sat): take a stroll through Cannaregio, explore the activities along Canal Grande, admire the striking features of Basilica di San Marco, then admire the landmark architecture of St Mark's Campanile, then examine the collection at Doge's Palace, and finally admire the masterpieces at Peggy Guggenheim Collection. Get ready for a full day of sightseeing on the next day: take in the architecture and atmosphere at San Giorgio Maggiore, appreciate the extensive heritage of Centro Storico di Venezia, wander the streets of Dorsoduro, then admire the landmark architecture of Scala Contarini del Bovolo, then appreciate the extensive heritage of Piazza San Marco, and finally take in the views from Ponte dei Sospiri.

To see ratings, where to stay, traveler tips, and tourist information, use the Venice driving holiday planner.

Traveling by car from Verona to Venice takes 1.5 hours. Alternatively, you can take a shuttle; or take a train. In April in Venice, expect temperatures between 21°C during the day and 11°C at night. Finish up your sightseeing early on the 30th (Sun) so you can go by car to Ravenna.

Famous for its wealth of original mosaics, Ravenna is a hub of artistic and cultural heritage.

Kick off your visit on the 1st (Mon): don't miss a visit to Mausoleo di Galla Placidia, contemplate in the serene atmosphere at Basilica di San Vitale, contemplate in the serene atmosphere at Battistero degli Ariani, then take in the spiritual surroundings of Battistero Neoniano (Battistero degli Ortodossi), then contemplate the long history of Basilica di Sant'Apollinare Nuovo, and finally contemplate in the serene atmosphere at Basilica Di Sant'Apollinare In Classe.

To see ratings, reviews, maps, and other tourist information, refer to the Ravenna trip itinerary tool.

You can drive from Venice to Ravenna in 2.5 hours. Alternatively, you can take a train; or do a combination of train and bus. In April in Ravenna, expect temperatures between 21°C during the day and 9°C at night. Finish up your sightseeing early on the 1st (Mon) so you can catch the flight to Rome.

Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.

Eschew the tourist crowds and head to Villa Borghese and Arcibasilica di San Giovanni in Laterano. Next up on the itinerary: explore the ancient world of Colosseum, explore the world behind art at Galleria Borghese, contemplate the long history of Palatine Hill, and don't miss a visit to St. Peter's Basilica.

For traveler tips, photos, where to stay, and more tourist information, go to the Rome online tour itinerary builder.

Fly from Ravenna to Rome in 2.5 hours. Alternatively, you can take a train; or drive. Expect a daytime high around 28°C in May, and nighttime lows around 17°C. Finish your sightseeing early on the 4th (Thu) so you can travel to Capri.

The island of Capri encompasses all the magical allure of the Mediterranean--dramatic blue waters, lush mountainous landscape, and picturesque island villages.

Kick off your visit on the 5th (Fri): surround yourself with nature on Nesea Capri, admire the natural beauty at Giardini di Augusto, explore the striking landscape at I Faraglioni, get engrossed in the history at Villa San Michele, then take in the awesome beauty at Monte Solaro, and finally stroll through Fortini Coastal Walk.

To find traveler tips, more things to do, where to stay, and other tourist information, refer to the Capri attractions planner.

You can do a combination of train and ferry from Rome to Capri in 4 hours. Alternatively, you can do a combination of car and ferry; or do a combination of bus and ferry. In May, daytime highs in Capri are 27°C, while nighttime lows are 18°C. Finish your sightseeing early on the 5th (Fri) so you can ride a ferry to Naples.

Naples is the capital of the Italian region Campania and the third-largest municipality in Italy after Rome and Milan. Start off your visit on the 6th (Sat): take in the pleasant sights at Lungomare Caracciolo, take an in-depth tour of Galleria Borbonica, contemplate the long history of Villa dei Misteri, then delve into the distant past at Parco Acheologico di Ercolano, then contemplate in the serene atmosphere at Museo Cappella Sansevero, and finally see the interesting displays at Museo Archeologico Nazionale di Napoli. Here are some ideas for day two: delve into the distant past at Pompeii Archaeological Park, make a trip to Lupanar, and then pause for some serene contemplation at Cloister of Santa Chiara.

To see where to stay, ratings, traveler tips, and tourist information, use the Naples trip planner.

Traveling by ferry from Capri to Naples takes 1.5 hours. In May in Naples, expect temperatures between 27°C during the day and 17°C at night. On the 7th (Sun), wrap the sightseeing up by early afternoon so you can fly back home.